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KMID : 0362919840020010107
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Journal of the Korean Society for Therapeutic Radiology and Oncology
1984 Volume.2 No. 1 p.107 ~ p.113
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Radiotherapy Result of the Carcinoma of Uterine Cervix
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Park Charn-Il
Ha Sung-Whan
Kang Soon-Beom
Lee Hyo-Pyo
Shin Myon-Woo
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Abstract
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One hundred sixty one patients with the carcinoma of uterine cervix received curative radiotherapy at the Department of Therapeutic Radiology, Seoul National University Hospital between December, 1979 and December, 1982.
According to FIGO classification; stage Ⅰa 1(0.6%), Ⅰb 8(5.0%), Ⅱa 31(19.3%), Ⅱb 66(41.0%), Ⅲa 3(1.8%), Ⅲb 46(28.6%) and Ⅳa 6(3.7%). The proportion of early stage cancer is too small because most of them treated by surgery.
External beam whole pelvic irradiation was done first with 10 MV x-ray or Co-60 gamma ray upto 4,000 or 5,000 rad for early and advanced cases, followed by one or two courses of intracavitary radiation using Fletcher-Suit Applicator loading c Cs-137. Supplementary external radiotion to pelvic side wall to bring dose to 6,000 or 6,500 rads, if there is paradmetrial involvement or positive pelvic lymph node.
Of the 161 patients, 49patients were lost to follow-up but only 22 patients were lost in disease free state. And so, 86.3 percent of the patients were followed to time of recurrence or to date.
The results are as follows;
1. Locoregional control rates according to stage is: stage Ⅰ 100% Ⅱa 90.3%, Ⅱb 75.8%, Ⅲa 66.7%, Ⅲb 58.7% and Ⅳa 16.7%, respectively.
2. Persistent or recurrent disease were localized in pelvic cavity in 32 of 50 patients and 6 had distant metastasis only.
3. Rectal bleeding was the most common complication and appeared mostly between 6 and 24 months after radiotherapy. Most of them had transient minor bleeding and only 2 patients needed transfusion and 1 patient needed colostomy due to rectovaginal fistula.
4. The 3 year disease free survival rate is: stage Ⅰ 100%, Ⅱa 78.0%31(19.3%), Ⅱb 60.6%, Ⅲa 66.7%, Ⅲb 46.3% and Ⅳa 16.7%, respectively.
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